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                                                                                                                                                                                                  )                                                                                                                                                      	                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          	                            
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                        +         #                   )   }   o      &               f                                                                                                                                                                    )                                                                      	                                                                                                                                                                                                                                        	            
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           	              $      	        
         	   
   
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        +   #       ) } o  &     f   |œ  }¶  }Ð  ~   ‚¦  ‡l  �è¾ŽZòDýnc$DJ
„Ê,Leîœ®TkCd¬”J Ñ	'¸¿ö
'Y�
œÍ
™ÞMÇx˜;Þ´´”ùn¶J
¾ MÇçkƒÌ%sN»9QŽ�ºÕón¶é8>6Š¡,2§Ëú†²I»ôx};‚R	[
éñKšR	ÐéêñR	éññšñ¢b8J×öþ�Tœ§<•‡ª2( (§�™ ¿„XžN
&ý² ¡K¢tHŠQ<¢žŸ¤sVl­L!ãžpr§ú´œaBŸ©âH
Ý”Ú‡äÊ”>`Ú²<DgŒÒÓ¨VÞGMç\Å	ç•7ëŠ~ çÿ§Ê	¿Æ×	6Âr›	°r§ú´DQœ‹ã ÃC	Œø  -šdÂ²pÆL¡ dÆ¡ˆRÿ \)¦á±s�î~®W ?dRhÆ¡Å	• -š7´
ÂRGk®•9žD_à'P5s»Öw·{]Qd¦ÿ3jÐ¿
†v•T÷ÆÎD€ fÊ” >`Ú³
ÏR²'<WŸDgŒªÑÒ0Y,z¾x¹½c[üÚW~ÌöruXqÁÆ
IKºî	csaô
ªS›9sˆèõ‡,Þ
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ç5Ýu
aõÍ  -š?7´
dÂRGkh²p®ÆL¡%*YIÃC	ŒaasõK¢tw Mz~®Õ!P9coJW€15ÃÑü`s¨»Ù“n°¶ÒÖÿ9T»ØE›Àítaô
õÃPC	L	`5s»ÖŒKî	  f¡ðæn
kwwˆÏ úVÝoc»•	�Fö"JÙ·«ˆô
…2Y~‘EYFó£æûÔfŸ-šÂ¾Æ×	6Ârx›	¹½c[°^¦$ò˜ÿu½âç BŸŽ6Ú	� ç Àa)/B±áGd`—¨Æ«¡Ÿ  Í ÛbÇžºÏ%G£„	u
¾*T©V’›î&R¬ÍÈuû]¿Y\I  ã Ja ‘ü9TÍô
`e­ÚàÕ8�Ð¿
vÍe­ÚBŸ‹ÚW~Ìöür(Žš Zö¥¤Ñ4l¯ï?Ï) Ò"Cv‡#
ä5|LŽ¶	¦`¤Ÿ  ¡¹ðæn
kw ¡?_ÃxH‰RÓ«T‹œÇ‡§ -¦YFqÁyÑÆ
­IÇ ÌÏÒ+¾
¯‚¬Õ2µ™Ü-?â#&ñ9§Ø LRSkI0�nˆ‰HèM¼e€#û
YàÑ¤v\ÿqTÂI�nÌÒ¯‚¬µ™#&ñ§Ç Ï+¾
Õ2Ü-?â9â…në*¦Åò\Ñ}î:ßr+; Ç ÌÏÒ+¾
‹™¯>é(‚‡¬Õ,/2~§µ'™Ü-?B¸Sâ#&ñ9Œ§ëRÓ«T‹œˆ‰HèÇM‡§ -¼sqáÜw¿g§º¸äýµ8 hþ
?%$üÏN½×¹Ñ,ÝI  xÞù	
 Ä¡4ªÕŒm<>³|•[or×ìò§Æ& ò>“·p¢O
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Ÿ5Ûl ¢èUKÜ÷š1Ùq	ÎâOP˜ØC½þ<^„p¾}¿3Ÿf­ƒ¹¼& l ³ ò'>“·Õp¢7	O
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<Created UTC="16:0:0">2017.6.5</Created>
<LastModified UTC="7:33:51">2019.10.29</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
</Notes>
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  @<Notes>
<UUID>4ff05e09-b66c-469c-8065-75f8cff75ce8</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<Created UTC="16:0:0">2017.6.5</Created>
<LastModified UTC="7:33:44">2019.10.29</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
</Notes>
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arrow indicates direction of (+) strand synthesis&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="5" name="CMV enhancer" type="enhancer" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="235-614" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;human cytomegalovirus immediate early enhancer&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="6" name="SV40 promoter" directionality="1" type="promoter" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="3898-4227" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;SV40 enhancer and early promoter&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="7" name="bGH poly(A) signal" type="polyA_signal" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="3186-3410" color="#a6acb3" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;bovine growth hormone polyadenylation signal&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="8" name="CMV promoter" directionality="1" type="promoter" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="615-818" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;human cytomegalovirus (CMV) immediate early promoter&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="9" name="SV40 ori" type="rep_origin" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="4078-4213" color="#ffff00" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;SV40 origin of replication&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="10" name="SV40 poly(A) signal" type="polyA_signal" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="5262-5383" color="#a6acb3" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;SV40 polyadenylation signal&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="11" name="AmpR promoter" directionality="2" type="promoter" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="7451-7555" color="#ffffff" type="standard"/><Q name="gene"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;bla&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="12" name="3xFLAG" directionality="1" translationMW="2730.72" type="CDS" allowSegmentOverlaps="0" cleavageArrows="3148" consecutiveTranslationNumbering="1" maxRunOn="3151" maxFusedRunOn="3151" detectionMode="exactProteinMatch"><Segment range="3083-3148" color="#cc99b2" type="standard" translated="1"/><Q name="codon_start"><V int="1"/></Q><Q name="product"><V text="&lt;html&gt;&lt;body&gt;three tandem FLAGÂ® epitope tags, followed by an enterokinase cleavage site&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="transl_table"><V int="1"/></Q><Q name="translation"><V text="DYKDHDGDYKDHDIDYKDDDDK"/></Q></Feature><Feature recentID="13" name="lac promoter" directionality="2" type="promoter" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" visible="0"><Segment name="-10" range="5480-5486" color="#ffffff" type="standard"/><Segment range="5487-5504" color="#ffffff" type="standard"/><Segment name="-35" range="5505-5510" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;promoter for the &lt;i&gt;E. coli lac&lt;/i&gt; operon&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="14" name="CAP binding site" type="protein_bind" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" visible="0"><Segment range="5525-5546" color="#31849b" type="standard"/><Q name="bound_moiety"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;E. coli&lt;/i&gt; catabolite activator protein&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;CAP binding activates transcription in the presence of cAMP.&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="15" name="T7 promoter" directionality="1" type="promoter" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1"><Segment range="863-881" color="#ffffff" type="standard"/><Q name="note"><V text="&lt;html&gt;&lt;body&gt;promoter for bacteriophage T7 RNA polymerase&lt;/body&gt;&lt;/html&gt;"/></Q></Feature><Feature recentID="16" name="lac operator" type="protein_bind" swappedSegmentNumbering="1" allowSegmentOverlaps="0" consecutiveTranslationNumbering="1" visible="0"><Segment range="5456-5472" color="#31849b" type="standard"/><Q name="bound_moiety"><V text="&lt;html&gt;&lt;body&gt;&lt;i&gt;lac&lt;/i&gt; repressor encoded by &lt;i&gt;lacI&lt;/i&gt;&lt;/body&gt;&lt;/html&gt;"/></Q><Q name="note"><V text="&lt;html&gt;&lt;body&gt;The &lt;i&gt;lac&lt;/i&gt; repressor binds to the &lt;i&gt;lac&lt;/i&gt; operator to inhibit transcription in &lt;i&gt;E. coli&lt;/i&gt;. This inhibition can be relieved by adding lactose or isopropyl-Î²-D-thiogalactopyranoside (IPTG).&lt;/body&gt;&lt;/html&gt;"/></Q></Feature></Features>
   —<?xml version="1.0"?><Primers nextValidID="0"><HybridizationParams minContinuousMatchLen="10" allowMismatch="1" minMeltingTemperature="40"/></Primers>
   <Notes>
<UUID>4e19bc13-252d-4e66-98bb-eb79ca563d0e</UUID>
<Type>Synthetic</Type>
<ConfirmedExperimentally>0</ConfirmedExperimentally>
<CustomMapLabel>pCDNA3.1-USP44-3Ã—FLAG</CustomMapLabel>
<UseCustomMapLabel>1</UseCustomMapLabel>
<Created UTC="16:0:0">2017.6.5</Created>
<LastModified UTC="9:27:27">2025.8.27</LastModified>
<SequenceClass>UNA</SequenceClass>
<TransformedInto>unspecified</TransformedInto>
</Notes>
  Y     K         
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   )<?xml version="1.0"?><CustomEnzymeSets/>
